Itch is one of the most underestimated skin symptoms, but one of the most challenging for people to live with. And when your skin is itchy, what you really want is fast relief in the form of something comforting and soothing to apply.

That’s why we created our new medicated calming lotion, Anti-Itch Solution: It’s a steroid-free moisturizing lotion that alleviates itching associated with minor burns and cuts, sunburn, scrapes, and insect bites. Beyond providing essential relief from 1% pramoxine hydrochloride, it’s a lightweight, silky formula that absorbs easily to soothe—while allantoin, shea, avenanthramides, and a multi-ceramide blend hydrate and nourish.

Anti-Itch Solution Key Dermatological Ingredients

The Active Ingredient

• 1% pramoxine hydrochloride: temporarily relieves itching associated with minor skin irritations

The Skin-Supporting Ingredients

• Allantoin: moisturizes and soothes
• Multi-Ceramide Blend: increases hydration and supports barrier function
• Dimethicone: smooths skin and enhances glide

What Is Pramoxine Hydrochloride?

Anti-Itch Medicated Calming Lotion is formulated with 1% pramoxine hydrochloride, which is an FDA-approved active that temporarily relieves itching associated with minor skin irritations.

It's an external analgesic: It works to relieve pain and itching by depressing cutaneous sensory receptors. In other words, pramoxine hydrochloride interrupts nerve signals before they reach your brain.

At 1%, pramoxine hydrochloride provides temporary relief of pain and itching associated with minor burns, sunburn, minor cuts, scrapes, insect bites, minor skin irritations and rashes due to poison ivy, poison oak, or poison sumac.

Anti-Itch Solution Medicated Calming Lotion Benefits

• Quick-absorbing, lightweight formula ensures comfortable application and wear
• Contains 1% pramoxine hydrochloride to soothe skin with effective steroid-free relief
• Enriched with a multi-ceramide blend to help boost hydration and support barrier function
• A blend of soothing, nourishing ingredients help calm skin sensitivity

What Types of Itch Does Anti-Itch Solution Help Relieve?

Anti-Itch Solution provides temporary relief of pain and itching associated with:

• Minor burns
• Sunburn
• Minor cuts and scrapes
• Insect bites
• Minor skin irritations
• Rashes due to poison ivy, poison oak or poison sumac

How Quickly Does Anti-Itch Lotion Work?

Anti-Itch Medicated Calming Lotion is fast-acting and works within minutes. When you need it, just apply directly to the affected area (no more than 3 to 4 times a day).

Pramoxine Hydrochloride vs Hydrocortisone

Pramoxine Hydrochloride is an external analgesic, which means it’s a steroid-free, topically applied drug that relieves pain by depressing cutaneous sensory receptors. Hydrocortisone is a type of topical steroid that works by decreasing inflammation in your skin.

How Do I Incorporate Anti-Itch Lotion Into My Routine?

Just apply Anti-Itch Solution to skin, wherever you need temporary relief from pain and itching.

Can You Use Anti-Itch Lotion Daily?

Adults and children 2 years and older can apply Anti-Itch Medicated Calming Lotion to any affected area not more than three to four times daily. Ask a doctor if your condition worsens or symptoms persist for more than seven days (or clear up and occur again within a few days).

How Anti-Itch Lotion Differs From Barrier Therapy

Both Anti-Itch Solution and Barrier Therapy are soothing, moisturizing, and temporarily relieve itching. But they work through different mechanisms and each serve a distinct purpose.

Anti-Itch Solution is a medicated calming lotion that temporarily relieves pain and itching associated with minor skin irritations, including minor burns, sunburn, minor cuts and scrapes, insect bites, minor skin irritations, rashes due to poison ivy, poison oak and poison sumac. Its active ingredient is 1% pramoxine hydrochloride, which works to relieve pain topically by interrupting nerve signals to the brain.

Barrier Therapy is a skin protectant cream. (Skin protectants are over-the-counter moisturizers formulated with FDA-recognized active ingredients that temporarily protect compromised skin and reduce moisture loss.) Its active ingredient is 1% colloidal oatmeal, which temporarily alleviates itchiness and minor irritation due to dry skin and eczema.

If you deal with itchy skin, even occasionally, this medicated lotion is a useful lotion to have on hand. And Anti-Itch Solution is exactly how medicated skincare should feel: effective, comforting, and thoughtfully formulated.

DISCLAIMER: All skin care articles are intended to help educate on specific ingredients and skin care topics. Our articles are written to be informative and informational. Any reference to a specific patient experience is not a medical suggestion for treatment. Please note that any Prequel products with referenced ingredients are formulated for Cosmetic Use Only and NOT intended as replacements for physician advice and/or pharmaceutical product recommendations.