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Welcome to Prequel's Skin Notes skincare blog. We’re passionate about skin health education. Skin Notes is a collection of articles that focus on skincare concerns, ingredients, technologies and more.
hypochlorous acid for skin

Hypochlorous Acid in Skincare

Hypochlorous acid is a powerful oxidizing agent that can help reduce bacterial bioburden on the skin to address topical systems of congestion and rosacea. Also helps improve the overall health and appearance of skin by soothing and calming irritated or damaged skin.

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allantoin for skin

Allantoin in Skincare

Allantoin is a compound that can be found in several plants, such as comfrey, chamomile, and wheat sprouts. In topical medical treatments, it's used to promote wound healing and in skincare, allantoin is recognized for its soothing, moisturizing and keratolytic (skin-softening) properties. 

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adenosine in skincare

Adenosine in Skincare

Adenosine, a bio-organic compound found in every cell of our bodies, has gained recent recognition in the skincare industry for its topical restorative and skin-soothing properties. Particularly effective in reducing the appearance of fine lines and improving skin elasticity, adenosine is a promising ingredient for those seeking to achieve overall healthier looking skin.

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Dr. Sam Ellis’ Essential Skincare Ingredients

Dr. Sam Ellis’ Essential Skincare Ingredients

Achieving healthy and radiant skin is a common aspiration, and it all begins with understanding the transformative potential of key skincare ingredients. In this blog post, we will explore a curated selection of powerful ingredients that have earned recognition from dermatologists for their remarkable benefits.

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urea in skincare

Urea in Skincare

A hygroscopic molecule (capable of absorbing water) naturally present in the skin that helps support skin barrier function and enhance water binding capacity. For skincare, urea is synthesized in labs to be effective in treating dry, rough, and scaly skin conditions. It can act as a humectant, emollient and/or exfoliant depending on percentage of use and format.

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glycerin for skin

Glycerin in Skincare

Glycerin is a cosmetic ingredient and OTC skin protectant that has been well studied and is widely used as a humectant. It is known for its ability to improve skin hydration, enhance cutaneous elasticity, and restore the epidermal barrier.

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dimethicone in skin care

Dimethicone in Skincare

Dimethicone is a cosmetic ingredient and OTC skin protectant commonly used for its sensorial aspects in addition to helping the skin stay hydrated, soft, and supple. Due to its large molecular weight it forms a barrier on the skin’s surface to keep in water and protect it from irritants.

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petrolatum for skin

Petrolatum in Skincare

Petrolatum is a cosmetic ingredient and OTC skin protectant used as an occlusive agent. It creates a protective barrier on the skin's surface that helps to prevent moisture loss and protect the skin from external irritants.

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cica for skin

Cica in Skincare

Cica is a medicinal herb known for its topical soothing, rejuvenating and moisturizing properties. Effective in calming inflamed and sensitized skin to achieve a more balanced skin barrier.

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feverfew in skincare

Feverfew in Skincare

Feverfew is an extract known for its antioxidant and anti-inflammatory properties. Used in skincare for its soothing effects and to help alleviate irritation and topical redness, making it suitable for sensitive and reactive skin types.

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DISCLAIMER: All skin care articles are intended to help educate on specific ingredients and skin care topics. Our articles are written to be informative and informational. Any reference to a specific patient experience is not a medical suggestion for treatment. Please note that any Prequel products with referenced ingredients are formulated for Cosmetic Use Only and NOT intended as replacements for physician advice and/or pharmaceutical product recommendations.


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