Polyglutamic Acid Description

Polyglutamic acid is a non-exfoliating natural moisturizing peptide proven to be a better hydrator than hyaluronic acid and collagen protein as it helps restore skin elasticity, smooth visual wrinkles, and increase production of NMF. This anionic soothing polymer can also help provide skin smoothness and protection against external aggressions.

With the ability to hold up to 5000 times its weight in water, PGA also provides unparalleled hydration, leaving your skin plump and radiant. It enhances skin elasticity and reduces fine lines. Perfect for all skin types, PGA also strengthens the skin barrier, revealing a smoother, more youthful complexion.

By inhibiting hyaluronidase, PGA preserves the skin's intrinsic hyaluronic acid. For maximum moisture benefits, PGA can be used under your moisturizer or occlusive cream can be applied on top to “seal in” the benefits.

What Does Polyglutamic Acid Do To the Skin?

Polyglutamic acid is a powerful humectant that draws and bonds moisture to the skin’s top layers, thereby creating a barrier on the surface of the skin that prevents transdermal water loss. Due to its highly effective hydrating properties and its ability to seal in moisture, PGA reinforces the skin barrier, and it furthermore stimulates the skin's natural hydration system and collagen production processes.

Polyglutamic Acid Benefits

Polyglutamic acid saturates the skin with moisture, which smoothes the appearance of fine lines and wrinkles, improves skin elasticity and texture, and aids in the overall plumpness of the skin. These effects make it an ideal choice for targeting the effects of aging. Fortunately, PGA is generally well-tolerated by all skin types.

PGA is known to play well with other ingredients and can even amplify the performance of other humectants. Additionally, PGA has been shown to inhibit the effects of hyaluronidase, which is a naturally occurring enzyme that contributes to the breakdown of hyaluronic acid in the body.

Its lightweight, non-oily texture allows polyglutamic acid to be layered successfully with other serums, moisturizers, sunscreens (such as our Sun Barrier Mineral Sunscreen Broad Spectrum SPF 50 PA++++), and makeup.

Can You Use Vitamin C and Polyglutamic Acid Together?

Polyglutamic acid is safe, and even recommended to use with both Vitamin C and Vitamin A products. Moisture balanced skin will actually respond better to stronger active serums to help reduce any potential intolerance and irritation so for best results use our Multi-Quench Polyglutamic Acid Serum along with your favorite active serum. The Prequel Lucent-C Brightening Vitamin C Serum is a great partner to help increase radiance and firmness, as well as to combat free radicals. Dr. Sam Ellis recommends applying the Lucent-C Brightening Vitamin C Serum, follow with the Multi-Quench Polyglutamic Acid Serum, and for those with an inclination to visual redness, wait 30 seconds and apply our Redness Reform Serum.

DISCLAIMER: All skin care articles are intended to help educate on specific ingredients and skin care topics. Our articles are written to be informative and informational. Any reference to a specific patient experience is not a medical suggestion for treatment. Please note that any Prequel products with referenced ingredients are formulated for Cosmetic Use Only and NOT intended as replacements for physician advice and/or pharmaceutical product recommendations.