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Welcome to Prequel's Skin Notes skincare blog. We’re passionate about skin health education. Skin Notes is a collection of articles that focus on skincare concerns, ingredients, technologies and more.
shea butter in skincare

Shea Butter in Skincare

Shea butter is a tree-nut-derived emollient that is rich in unsaponifiables and is also a natural source of vitamin E. Utilized in skin care to help soothe, moisturize, and visually improve dry or compromised skin.

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arginine in skincare

Arginine in Skincare

Arginine is an amino acid part of the natural moisturizing factor (NMF) that adheres to skin due to its cationic charge. It provides long-lasting hydration and in a surfactant system reduces skin dryness.

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Kojic Acid in Skincare

Kojic Acid in Skincare

Kojic acid is a by-product of the fermentation process of certain types of fungi known for its skin-lightening properties. Effective in treating hyperpigmentation and age spots for a brighter, more even skin tone.

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ellagic acid in skincare

Ellagic Acid in Skincare

Ellagic acid is a naturally occurring polyphenol with potent antioxidant and skin-brightening properties. Effective in protecting the skin from environmental damage and reducing the appearance of dark spots.

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lactic acid in skincare

Lactic Acid in Skincare

Lactic acid is a type of AHA that gently removes the top layer of dead skin cells to help improve skin texture, reduce dark spots, smooth fine lines, hydrate, and improve skin complexion.

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Vitamin K in Skincare

Vitamin K in Skincare

Vitamin K is a fat-soluble vitamin hailed for its potential in promoting skin health by accelerating the skin's healing process and improving various skin conditions, including dark circles, rosacea, and spider veins.

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azelaic acid for skin

Azelaic Acid in Skincare

Azelaic Acid is a dicarboxylic acid, different from alpha hydroxy acids and beta hydroxy acids, that acts as a “skin balancing ingredient” to address bioprocesses that are overreacting. It normalizes skin pigmentation, decreasing hyperpigmentation.

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sulfur in skincare

Sulfur in Skincare

Sulfur is a cosmetic ingredient and OTC acne active that is used to reduce sebum production, acne blemishes and the appearance of scars due to its ability to exfoliate. Sulphur acts as a keratolytic agent that can loosen the connection between the skin cells.

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Retinaldehyde in Skincare

Retinaldehyde in Skincare

Retinaldehyde is a part of the retinoid family closest to retinoic acid on the conversion scale, making it more potent and bioavailable than retinol. It helps improve skin elasticity, increase gene expression for collagen synthesis, and visually reduce facial wrinkles.

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DISCLAIMER: All skin care articles are intended to help educate on specific ingredients and skin care topics. Our articles are written to be informative and informational. They are not indicative of individual performance. Results may vary per applicant. Any reference to a specific patient experience is not a medical suggestion for treatment. Please note that any Prequel products with referenced ingredients are formulated for Cosmetic Use Only and NOT intended as replacements for physician advice and/or pharmaceutical product recommendations.


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